CYSTIC GASTRIC STROMAL TUMOR NEGATIVE C-KIT Tumor estromal gástrico cístico c-kit negativo

Gastrointestinal stromal tumors (GIST) are rare, representing less than 1% of all gastrointestinal tumors. However, this is the most frequent nonepithelial neoplasm of the digestive tract. Mean age at diagnose is 58 years old, and the two structures usually involved are stomach and bowel12. The main symptoms are abdominal pain and digestive bleeding2, while the most frequent presentation are solid tumors11. Diagnose is confirmed by histology and imunohistochemistry analyses, followed by CD117 analyze which is positive in about 95% of cases7. The preferred initial treatment is surgical excision. Recently, the introduction of imatinib mesylate, a monoclonal antibody, has brought great advances in the adjuvant therapy for these patients, especially in tumor control when the primary lesion was locally advanced9. This is a case of gastric GIST predominantly cystic with negative c-Kit, but CD-34 positive, successfully treated by laparoscopic surgery.